RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-22
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR; immunofluorescence etc.
Target
CAV3
Pathway
CALCIUM SIGNALING PATHWAY
PubMed ID
Title
Abnormal Downregulation of Caveolin-3 Mediates the Pro-Fibrotic Action of MicroRNA-22 in a Model of Myocardial Infarction
Year
2018
Function
Ir-22 accelerates cardiac fibrosis through the miR-22-CAV3-PKC pathway.